worst days on taxotere

As I have not had much of an appetite due to mouth issues, I had constipation but once that passed I have had loose bowels. Doreen D. (Breast Cancer, Invasive Ductal Carcinoma, Stage 2A,Triple Positive). Hope you are all doing well with your journey and keeping well. Your red blood cells are responsible for carrying oxygen to the tissues in your body. I took Oestrogen suppressing tablets over July and August and restarted chem beginning of September with the FEC. Avoid contact sports and activities that can result in injury or bleeding. 4 days after having it I was so sick I could not go to work. Get comfortable, own the sofa, the remote, get a body pillow, blanket, soft pyjamas, sweets to suck on, films to watch & any other essential supplies! A little morning nausea for first week, a few headaches and sore lips. (2013) demonstrated that nano-formulation improved plasma PK and tumor delivery of Doc compared to the unprocessed Doc. Patients may struggle with never-ending itchiness, swollen eyelids, and an increase in floaters. They might also encounter infections and inflammatory disorders as a result. Paracetamol Ibuprofen/codiene didn't work. I was 'tired' on days 3 & 4 on A/C but napping/resting helped. But by my third week I felt somewhat normal, would tire quick but normal. Then I will start on radiotherapy. 10 year old is self sufficient. One of the common types of chemotherapies for breast cancer, AC + T includes three drugs: doxorubicin (Adriamycin), cyclophosphamide (Cytoxan), and a taxane drug (Taxol, Taxotere . So close to week three now, exercise nil, so bored with all the sofa days. Most of the hard work is done, you just need to push a little harder to finish the race! The mouth issues I suffered with all the way through chemo (didn't have thrush) but would say the mouth part was my worst SE. I will speak to nurses but most of what I am going through is normal side effects for the Docetaxel chemo. Found the freeze gell hit the joint areas better and gave relief. I have weaned myself off the Co-Codamol as I don't want to rely on it and the bone aches have reduced considerably now. I just had my first Docetaxal dose over a week ago.. Have you rang your chemo hotline? Saying goodbye to our 8th graders and saying" Not sure this helps at all but as your op was so successful (and you must still be recoverying from the trauma of all that too) will hope that the treatment now will keep you well in the long term. On Taxol I was comnpletely exhausted on days 2 - 6 and napping/resting did not help at all. A week in hospital on IV antibiotics and fluids and I was allowed home to rest rest rest! Fatigue. Do not floss or use toothpicks and use a soft-bristle toothbrush to brush your teeth. We have each other even if we don't know each other. Talk to your oncology care team so they can prescribe medications to help you manage nausea and vomiting. The one time I threw up was after my second round. xx, No problem you keep strong & you will get through it, I've never cried so much in my life I think it was my way of dealing with it. Please. I think I am coming to the end of feeling like I have hit by a bus with the chronic aches in all my joints and bones. Some common Taxotere side effects include: Heres what cancer patients had to say about their experiences with Taxotere: I started chemotherapy. Most people notice that their neuropathy gets better 2 to 4 months after chemotherapy, but it can take up to 1 year to fully go away. So going through the rest of the horror. Grapefruit can change how your body absorbs this medication. I was informed that I would need a mastectomy as to the way the tumour is growing in the breast. Thanks for being such a grand support for her. You may use nail polish, but do not wear fake nails. I was better prepared for the following two though. Docetaxel is normally given once every three weeks, over about one hour. Your nurse will check you for signs of a reaction during your treatment. I had four rounds of Herceptin, Carboplatin, and Taxotere. Perseverance!! It really helped me that there was a gap between the two sets of chemo cycles, gave me a chance to recover a bit from the taxotere before starting the treatments again. Some brief shopping time to restock for the next session. These are some of the most common or important side effects: Allergic reactions are possible with this medication. These Taxotere side effects are less common, meaning they occur in 10-29 percent of patients receiving Taxotere: Vomiting Muscle/bone/joint pain (myalgias and arthralgias) Low platelet count (This can increase your risk of bleeding) Increases in blood tests measuring liver function. In 2022 . Actually, I had a really nice time as it was. It was neoadjuvant chemotherapy, including Taxanes (Taxotere), Carboplatin, and Trastuzumab (Herceptin). Even my vision has been effected. Overall I did find the T harder than Fec but others say they found it the other way around so it's just pot luck really. X. Hi everyone, I start taxatere in feb.can anyone please tell me If I have to have the horrid injections for bone marrow while having that chemo? Avoid things that may worsen the symptoms, such as heavy or greasy/fatty, spicy or acidic foods (lemons, tomatoes, oranges). Best of luck to you all xxx, I would be happy to receive news and updates from Cancer Chat, NICE suspected cancer referral guidelines, Cancer Research UK for Children & Young People. I was advised to take paracetamol (or cocodamol if you can bear it) and ibuprofen together every 4 hours from the third day after you have the chemo until the pain eases off, which for me was about day 10. My doctor did reduce the docetaxen for me after the first one e and it made a difference, My advise is phone your doctor or key worker and ask if them if they can reduce the doseage. It happens most often in the legs and feet, but it isnt unusual to see swelling in the hands, arms, and abdomen. Do not take aspirin (salicylic acid), non-steroidal, anti-inflammatory medications (NSAIDs) such as Motrin/Advil (ibuprofen), Aleve (naproxen), Celebrex (celecoxib), etc. I know everyone is different. You won't be up to doing anything. 2.6 Premedication Regimen. However, as more people used the drug, it was clear that the manufacturers hid that some side effects of Taxotere were permanent. But by the sound of it a lot of you needed that third week to recover, she won't have that. In the adjuvant treatment of operable node-positive breast cancer, the recommended TAXOTERE dose is 75 mg/m2 administered 1-hour after doxorubicin 50 mg/m2 and cyclophosphamide 500 mg/m2 every 3 weeks for 6 courses. Leg pain also bad tonight, I am on day 5 after first Taxotere chemo so I suppose it's working at its height at the moment, hope it gets better in the coming days! My wonderful wife took me away between chemo and Rads, it was a truly enjoyable break, 5 days in a cabin in the woods (provided free by The Willow Foundation). some were bad and some were tolerable plus i also had insomnia because of the steriods.Tell Donna to hang in thereand good luck to you Bob! But as I say.. We're now closer to the end.. 2 more to go.. Then an operation for me And immunotherapy for a year but chemo and op are the big ones to get over.. You'll get through it.. And there is life after chemo. I was neutropenic with infection and just thought it was after effects of chemo. Certain cancer treatments can cause sores or soreness in your mouth and/or throat. I completed 4 doses of EC (1 every 3 weeks). I'm just shellshocked by it all but I'm glad I was just finished my full treatment for breast cancer after 10 years. I used Clariton (over the counter) to combat the bone aches from chemo and the injection. His consultant advised small walks to begin the process of getting the muscles going (started with walking up and down our lounge before he managed the outside!! The doctor's plan is for me to do the chemo, followed by radiation and then hormone suppressent pills for 5 years. I had my first Taxotere on Monday and am not coping at all. Eyes watery but ok. Week Three was Im actually feeling pretty good and then you go right back to Week One. It was stage Three I though thats it,the end. Taxotere is part of a family of drugs known as taxanes that work by preventing cell growth. My reaction to Taxol was different. I was diagnosed in August with Breast cancer. Doctors may lower the dose or prescribe drugs that reduce the risk of allergic reactions to deal with these types of side effects. I am hopeful that the next two cycles will be less of a shock to the system. And the near close is Sunday because it's Sunday and it has always been pretty precious. (9.3%) in the vinorelbine+cisplatin arm. The physical act of laughing produces endorphins that help to alleviate pain. I end up with wet pillows at nightnever had that with Tamaxifen or in 50s. starting at end of cisplatin infusion (2.4)See full prescr ibing information for TAXOTERE. Cyclophosphamide is a type of chemotherapy medicine . Plan times to rest during the day and conserve energy for more important activities. HI Multitasker! I had infusions every 21 days. Avoid drinking alcohol on the day of your Taxotere injection. I still have a mountain to climb with surgery and radio therapy but it can't be any worse than this. This may vary depending on whether the number of blood cells has returned to normal between each cycle. Docetaxel is a microtubule inhibitor used to slow cell growth. But they had to keep treating her with antibiotics on the off chance it was an infection. Its just moving because I felt it moved the chemo through my body faster. Lets hope it does the trick and we can put this behind us. I got that too. So my advice is dont be scared to ring the chemo hotline, they know what to advise and whether or not you should go in.. She only took that a couple of times. Was 48mu for EC but took 7Tax was 30mu. I only have one more left now as it was my 5th cycle of chemo regimen FEC x 3 then Docetaxel x 3 . The effects from the chemo were still the typical things though. Got better on Day 6 and got better on Day 7. The effects of chemo are cumulative. Protein helped and exercise helped me. We've heard that the Taxol is a lot easier. The ASCO Genitourinary (GU) Cancers Symposium, which ended on February 18, 2023, was a three-day scientific and educational meeting designed to provide attendees with in-depth, multidisciplinary analysis of the timely topics in the study, diagnosis, and treatment of GU malignancies. Hope you are keeping well. Had tummy issues mostly diarrhoea but managed to get a good stopper tablet. Your oncology care team can recommend medications to relieve diarrhea. Do not use this information to diagnose or treat a health problem or disease without consulting with a qualified healthcare provider. If red meat is a problem, eat chicken, turkey, eggs, dairy products, and fish without a strong smell. Hope you are all enjoying the sunshine and feeling better. How many treatments is she having? Your Wife is unique! nausea and vomiting. Please consult with your healthcare team regarding the use of these agents and all over the counter medications/supplements while on therapy. Many women who receive taxane -based chemotherapy to treat breast cancer experience long-term peripheral neuropathy, according to follow-up data from a large clinical trial. Then starting in June 2014, I had 15 doses of Radiotherapy. Take care. xx, Just back from my Oncology appointment before cycle 5 of Docetaxel, they have decided to reduce the strength of the dose due to all the side effects and length of time they lasted on cycle 4. Is day 4 the worst day? You will have docetaxel as an outpatient. I need to focus on this and get back on track. I do have to rest far more than I used to, although I manage to cope with a busy full time job. Thank you, hope you continue to be well. While it sounds harmless enough, constantly tearing eyes can cause other health issues. My last infusion was in December. I have severe bloating which is so uncomfortable its almost painful. I had the FEC-T chemo first, from December 2013 to April 2014. The interval between each treatment gives your body time to recover. My skin, when I rub my fingers or touch my face, arms, legs etc feels different, almost plastic-y! Taxotere was my aggressive chemo, and it caused the majority of the side effects the hair loss, nausea, all these different things. Keep your fingernails and toenails clean and dry. This typically begins two to three weeks after treatment starts. 83 Likes, 0 Comments - Marley Foster (@marley._.foster) on Instagram: "The last few days of school were probably the worst. Let your oncology care team know if you have any excess bruising or bleeding, including nose bleeds, bleeding gums or blood in your urine or stool. This hair loss can be all body hair, including pubic, underarm, legs/arms, eyelashes, and nose hairs. Sore throat, swallowing, that was usually first couple of days then I started using Biotene (mouthwash)the day before chemo, the day of chemo, and the day after, and I didnt have any issues with that after at all. So would recommend this. It is used as a treatment for various cancers, most notably breast cancer. Worst days when i was on 3chemo meds, taxotere, carbon, and Herceptin, were 3-5 days after. By the second cycle,my nausea would start as Im getting my infusion. Make sure she is getting alot of water, eat fruits and vegetables. Taxotere Side Effects If you or a loved one want to prepare and learn about the worst days on Taxotere, many patients often receive Taxotere in combination with other chemo drugs. Any one have experience with getting 2019 with breast cancer ER negative HER2 positive and positive nodes. Thats Taxotere and Cyclophosphamide. Last reply: 8 years ago. Talk to your healthcare team for helpful tips on dealing with this side effect. Though chemo is officially kicking my butt, I want you all to know that I am determined to maintain my upbeat attitude and sense of humor through it all, no matter . I don't think you have "gone wrong" anywhere, more that T has hit you hard and you would like to be in a better place for the next 2. There is a risk that this medication may leak out of the vein at the injection site, resulting in tissue damage that can be severe. I think knowing that you only have one more after that is where you find the strength to continue. Men who are treated with this medication should use effective birth control during and for 4 months after the last dose. Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked. Nicole B. All content 2023 Trustees of the University of Pennsylvania. Brush with a soft-bristle toothbrush or cotton swab twice a day. Take care and we will get through this. I had the sore mouth too but I must have been one if the lucky ones as I do not remember too many other side effects - it was 7 years ago. Remember your hair helps keep you warm in cold weather, so a hat is particularly important in cold weather or to protect you from the sun. Medications will be given before each treatment to decrease the risk of this side effect. Chemotherapy kills regular cells, as well as cancer cells, and this is why side effects occur . Yesterday I finally got these problems under control. When working in your yard, wear protective clothing including long pants and gloves. A week later and I still can't get out of bed! Actual exercise. Treatment . You should let the oncology care team know if you experience numbness or tingling in the hands and/or feet, as they may need to adjust the doses of your medication. Know that you are two thirds of the way there. The only things I could taste were sweets. Progression-free survival was 2-3 months for both groups. Your healthcare provider can recommend medications and other strategies to help relieve pain. Signs of a reaction can include: shortness of breath or difficulty breathing, swelling of the face, lips, tongue or throat, trouble swallowing, chest pain, rash, flushing, hives or itching or a decrease in blood pressure. I am still needing sofa days, but hoping to get out soon for a much needed change of scenery and breath of fresh air. I am trying to keep focused and positive to get through this. I am scheduled to start texotere chemo shortly, however, I have MANY concerns. Shower or bathe daily and perform frequent. Found the freeze gell hit the joint areas better and gave relief. Taxol once every 3 weeks: 86.5% Taxotere once every 3 weeks: 87.3% Taxotere once a week: 86.2% Some doctors have wondered whether a taxane has benefits for women diagnosed with hormone-receptor-positive breast cancer. I followed all the advice and recommendations given by the medical team and tried to be positive about the treatment working to fight the cancer but it has been hard. The Docetaxel/Taxotere is the drug causing this nasty side effect. Your doctor may prescribe medication to take before your treatment to help decrease the risk of edema. Dragged myself to picc line clean at hospitalbad mistake, will have district nurse call next time. I took nausea tabs even when I wasn't nausaus, but it made little difference. As she feels better, your wife will realize that she CAN do it. You'll get there too. I have lost ALL taste buds. I mentioned this thread to her - the common wisdom that the first is the worst because of the uncertainty and the rest is more of the same, only more so. Can eat, not been sick, not taken antisickness meds, but nausia with ukky taste but poor sleep got worse. I also drank an ensure every day the week of chemothat does give you a boost. One of the most major Taxotere side effects is epiphora or, in simple terms, watery eyes. It will help clear it and make eating slightly more tolerable. Keep well. While on cancer treatment, and for a period after, you may need to adjust your schedule to manage fatigue. Recurrence of endometrial cancer in lymph nodes. Had a DIEP flap reconstruction in August 2016 and am currently waiting to get my date for another op to uplift and reduce my right boob to match the new one. The care I have had from diagnosis to today has been quick, I begin Radiotherapy begining of March. Re: Docetaxel help please!! I had constipation, diarrhea so bizarrely both, and then the nausea. Some chemotherapy medications can cause neuropathy (numbness or tingling in your hands and feet). I was severely feverish, my whole body ached to the point that I felt like I was in a can crushing machine, I felt sick and my mouth was worse than ever (it had been bad all the way through). You should let your doctor or nurse know if you experience any shortness of breath, difficulty breathing, or pain in your chest. We can do itnot sure how but we are two thirds there. If the platelet count becomes too low, you may receive a transfusion of platelets. For some people, it never completely goes away. I had cisplatin , taxotere and the neulastra shot and really hurt the 1st infusion but not the others after starting the clariton. Furthermore, the overall response rate for docetaxel in the intent-to-treat population (42.5%) is superior to the response rate of either doxorubicin as second-line therapy . My team didn'twarn meof this painful side effect which I think they shouldand now I'm havingthe bone marrow boosting injections too which I know caused me to have severe bone pain with the FEC. I've been prescribed Gabapentin, spoke to my oncologist after the first docetaxel. I had my last taxen (chemo) two weeks ago and felt okay the first three days and then it hits. Each day from now I knowI will get stronger and begin to do small task.Tthe feeling when I went for the last Chemo was a good I walked out and thought great I made it through now to get throught he effects. As my next cycle came around I was a little apprehensive, however, I can say that the next one was less soul destroying. I have at times reached my lowest and questioned if I can continue to put my body through this poison. If you notice any changes in how you feel during the infusion, let your nurse know immediately. xxx. But I know that's just wrong. The only really bad side effect I had was the fatigue. As horrid as her experience was, it had its payoff. I know the taste thing lasts for a while but I crave something good to eat. Can I just say thank you so much for the great advise, I am going through Taxotere part of chemo at the moment and it is just horrible, my poor hands are the worst, they are burning like mad but have been prescribed Piriton and paracetamol to try and rectify overnight and have to go to hospital in the morning that does seem to have helped. Keeping positive and looking forward to getting to the end of it all. So far I have been ok on the 2nd cycle just starting to feel the side effects kicking in this evening . Give yourself credit for getting this far. Sorry to be such a negative misery , I am usually upbeat and positive but wanted to ask if these cycles compound with the side effects as I am not sure I could cope with another 2 cycles. That seems to help me. I never threw up really, but I had underlying nausea all the time. You will have got through it now though? Ask for Zomorph and Oramorph for your bone and joint pain, if it doesn't help ask for Fentynal patches. Performing regular mouth care can help prevent or manage mouth sores. Letrazole and weird taste on tongue? DelveInsight has compiled the symposium's major highlights so that one does not miss out on these expansions . You should preferably avoid the regular consumption of grapefruits and grapefruit juice while taking DOCEtaxel. Patients may struggle with never-ending itchiness, swollen eyelids, and an increase in "floaters." The steroid is given in pill form or by IV, which will be determined by your healthcare provider. The infusion will be slowed or stopped if this occurs. For obvious reasons, Saturday is the best day of the week because it's a holiday and the next day too is a holiday, followed by Friday because it's preceded by two holidays. TAXOTERE was first approved for the F.D.A. Pineapple is good for helping the nasty taste and I know someone who sucked frozen pineapple cubes and this helped her a lot. Your nurse will check you for signs of a reaction during your treatment. All rights reserved. You should not breastfeed while receiving this medication or for 1 week after your last dose. You may experience a metallic taste or find that food has no taste at all. pathology report has our Onc ordering additional scans. I would go to work when I was able to and just did what I could. I actually postponed Rads for a few weeks so that we could go away. I had them for for all 3 Fec. So would recommend this. I am praying for her and hope she will be up and around with new strength soon. This combination of meds had the remarkable result of shrinking my very large tumor by a full 50 percent! Best wishes to everyone on this treatment and you will come out the other side. Sounds like you have had quite a week, similar to mine. Add extra flavor to meat or fish by marinating it in sweet juices, sweet and sour sauce, or dressings. She keeps telling me that she is not strong enough to do this; and I tell her that she is stronger than she thinks she is.Bob. Signs of a reaction can include: feeling hot or flushed shivering itching a skin rash feeling dizzy a headache feeling breathless or wheezy swelling of your face or mouth pain in your back, tummy or chest. She is also tired of taking pills. Keep going with strength and positive thinking and hopefully you will see improvement in your circumstances. Really sorry to read that you having such a s---- time with your current chemo treatment. It really helps to have these words of encouragement and support. This may increase the risk of side effects such as nausea, vomiting, diarrhea, mouth sores, fluid retention, nerve pain, numbness, tingling . My doctors have been very good and have assured me that they caught it early. I haven't had much information about that yet. I have a soup maker so maybe I should give it a go. I had the first T on Wednesday, was too sick to work come Monday, even worse come Thursday and in Hospital with Sepsis come Friday! Painkillers, she had all the same things as you. Call your healthcare provider if you do not urinate for more than 12 hours, experience shortness of breath, have an unexpected weight gain, or develop swelling in your hands, feet, ankles or legs. for me it was the 4th and 5th daysi had my first AC on June 10 (a Thursday), and the worst days for me were Sunday and Monday. It may get worse after you have your last chemotherapy treatment. My own experience to date As of day 8 after my first Tax blast, I currently hate Tax and FEC in equal measure. Gone too far now to stop just need to finish the course. I have other family and friends help but they have their own lives that need to go on. While it sounds harmless enough, constantly tearing eyes can cause other health issues. Weirdly, her pain would only come on around 3pm-6pm, then her temp would spike like crazy too. An absolutely horrid drug. After first AC on Wed. and doing "okay" Thurs. I am sorry that she is not feeling well. Sun sensitivity can last even after chemotherapy is completed. Thank you for the support, hope you are doing well. They also said that cycles 5 and 6 will compound the side effects and by reducing the dose the recovery should be quicker and help me to complete the chemo sessions. If you feel unwell or have any of these signs, tell them straight away. It, like other chemotherapy medications, can have severe side effects. For your mouth get som kingingical mouth wash and rinse with salt water every hour or so. Nutrition is an important part of your care. The prospect of 12 weekly taxol is a bit daunting. It had to have been that I just did too much. The content on this site is for informational purposes only. There are a number of things you can do to manage the side effects of docetaxel. Severe symptoms are less common but require dose modifications. love and hugs.Lorrie. If you do not have a bowel movement for 2-3 days, you should contact your healthcare team for suggestions to relieve constipation. Its common to lose hair when youre undergoing cancer treatments. (I too read somewhere that grapefruit can make the side-effects of the drug worse). x. I had the same treatment last year and just as you I struggled with Fec but my first T absolutely knocked me side ways! It has now been almost exactly 4 days (96 hours) since. Only better during the third week. I was prescribed preventative FEC-T but because I was getting married and honeymooning in July, they decided to do the Taxotere first and cycle 3 was combined with my whole radiotherapy treatment. It was tough going, but I got there. All patients should be premedicated with oral corticosteroids (see below for prostate cancer) such as dexamethasone 16 mg per day (e.g., 8 mg twice daily) for 3 days starting 1 day prior to TAXOTERE administration in order to reduce the incidence and severity of fluid retention as well as the severity of hypersensitivity reactions [see Boxed Warning, Warnings and . APAP vs. CPAP: Whats the Best Machine for Sleep Apnea? Except she would always end up in hospital as her temp would spike along with the joint pains. I think it would have been better to know just what to expect but as we all react different it's not possible. If it is hitting you hard hopefully the chemo will be kicking the cancer in the teeth. Will try the mouthwash as that is also a problem, I have a drink and seconds later my mouth is so dry again! Avoid any food that you think smells or tastes bad. Taxotere injections can cause serious and life-threatening fluid retention(edema). I'll be starting this Thursday and have 10 steroids to take Wednesday night and then whatever they give me as pre-meds. And there is no normal feeling throughout the 3 weeks. They didnt feel great, but it wasnt bad. We are all stronger than we think and even stronger than we give ourselves credit for! Yes you will have have to have the G - CSFinjections for the bone marrow stimulation after the Docetaxal chemotherapy - the same as the FEC. 1. Hopefully this will continue for the last 2 cycles. You may notice chills, a sore throat, achiness, and swollen glands and lymph nodes. I did everything I could. Genoa M. (Breast Cancer, Invasive Ductal Carcinoma [IDC], Stage 3, HER2+). She is on this dose denseShe is on this dose dense regiment; every two weeks; 4 rounds of AC followed by 4 rounds of Taxol (and I think it's five day after Nuelasta shots). In some cases, you might feel extra hungry or gain weight. The most common side effect in day-to-day life is fatigue. Today it was announced that his name would be on a car at Le Mans. This can get progressively worse with additional doses of the medication. I'm taking Codeine and paracetamol with little effect. Do not apply anything to the site unless instructed by your care team. Any comments, please. I got off lightly on the 4 AC, only had a couple of very bad days each cycle. I would have Gemcitabine on week one.

A Retrieved Reformation Lesson Plan, How Long After Mortgage Offer To Completion, Swimming Carnival Novelty Events, Law And Order: Organized Crime Unit Cast, Articles W